화학공학소재연구정보센터
Journal of the American Chemical Society, Vol.129, No.6, 1508-1508, 2007
Quantitative evaluation of the relative cell permeability of peptoids and peptides
We evaluated quantitatively the relative cell permeability of peptides and peptides using a cell-based reporter gene-based assay. Generally, peptoids were much more cell permeable than the corresponding peptides, though the difference decreased with increasing length. These results suggest that peptoids may be useful reagents for manipulating the activities of intracellular proteins.