Direct conversion of the pyrolytic vapor of radiata pine was conducted in a fixed catalyst bed reactor installed at the upper part of a bubbling fluidized bed reactor. The influence of different catalysts, the catalyst bed temperature, and the residence time of the vapor on the product distribution was investigated. The formation of char or tar in the fixed catalyst bed reactor could be inhibited through direct catalytic pyrolysis of the vapor of radiata pine over different catalysts. After catalysis, the bio-oil yield decreased while the gas yield increased. HZSM-5, in which strong acidic sites are properly distributed, was more efficient in bio-oil upgrading than HY; the oxygen in the bio-oil was largely converted into H2O, CO, and CO2. For Ga/HZSM-5, the bio-oil yield and the selectivity of aromatic hydrocarbons in the bio-oil increased.