Effects of desorbent flowrate on simulated moving bed process

Young-Il Lim

Korean Journal of Chemical Engineering, Vol.24, No.3, 391-396, May, 2007

DOI10.1007/s11814-007-0067-x Export Citation

Effects of desorbent flowrate on simulated moving bed process

Young-Il Lim^†

Department of Chemical Engineering, Hankyong National University, 67 Seokjung-dong, Anseong-si, Gyonggi-do 456-749, Korea

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This article presents the effects of the desorbent flowrate (or m1) on simulated moving bed (SMB) process performance at constant m2, m3 and m4, where the m-values (mj) are defined as the net flowrate ratios of the zone, j, to the solid flowrate. A complete m-plane analysis of SMB systems (ComPASS) has been developed that illustrates how the desorbent flowrate is determined within the complete m-plane (i.e., fluid-solid flowrate ratio plane) to enhance the SMB process performance. The effects of desorbent flowrate are presented numerically for linear/equilibrium and nonlinear/nonequilibrium SMB processes. The results of the studies using ComPASS show that for linear/equilibrium SMB process, it is desirable to determine the minimum desorbent flowrate (m1) within the complete separation region. For the nonlinear/nonequilibrium SMB process, the desorbent flowrate can be determined at the minimum value which maximizes the raffinate purity.

Keywords:Simulated Moving Bed (SMB) Chromatography;Desorbent Consumption;Triangle Theory;Process Simulation and Optimization;Complete m-Plane Analysis of SMB Systems (ComPASS)

[References]

Juza M, Mazzotti M, Morbidelli M, Trends Biotechnol., 18, 108 (2000)
Lim YI, Korean J. Chem. Eng., 21(4), 836 (2004)
Klatt KU, Dunnebier G, Hanisch F, Engell S, AIChE Symposium Series 326, 98, 239 (2002)
Mazzotti M, Storti G, Morbidelli M, J. Chromatogr. A, 769, 3 (1997)
Ludemann-Hombourger O, Pigorini G, Nicoud RM, Ross DS, Terfloth G, J. Chromatogr. A, 947, 59 (2002)
Ergun S, Chem. Eng. Prog., 48(2), 89 (1952)
Darby R, Chemical engineering fluid dynamics, Marcel Dekker, Inc., 2nd ed. Chapter 13, New York (2001)
Lim YI, Lee AL, AIChE Annual Meeting, San Francisco, USA, Nov. 12-17 (2006)
Chang SC, Courant number insensitive CE/SE schemes, 38th AIAA joint propulsion conference, AIAA-2002-3890, Indianapolis, USA (2002)
Lim YI, Chang CS, Jorgensen SB, Comput. Chem. Eng., 28(8), 1309 (2004)
Pais LS, Loureiro JM, Rodrigues AE, AIChE J., 44(3), 561 (1998)
Lim YI, Jorgensen SB, Chem. Eng. Sci., 59(10), 1931 (2004)

[Referenced By]

[Related Articles]

[1] Juza M, Mazzotti M, Morbidelli M, Trends Biotechnol., 18, 108 (2000)

[2] Lim YI, Korean J. Chem. Eng., 21(4), 836 (2004)

[3] Klatt KU, Dunnebier G, Hanisch F, Engell S, AIChE Symposium Series 326, 98, 239 (2002)

[4] Mazzotti M, Storti G, Morbidelli M, J. Chromatogr. A, 769, 3 (1997)

[5] Ludemann-Hombourger O, Pigorini G, Nicoud RM, Ross DS, Terfloth G, J. Chromatogr. A, 947, 59 (2002)

[6] Ergun S, Chem. Eng. Prog., 48(2), 89 (1952)

[7] Darby R, Chemical engineering fluid dynamics, Marcel Dekker, Inc., 2nd ed. Chapter 13, New York (2001)

[8] Lim YI, Lee AL, AIChE Annual Meeting, San Francisco, USA, Nov. 12-17 (2006)

[9] Chang SC, Courant number insensitive CE/SE schemes, 38th AIAA joint propulsion conference, AIAA-2002-3890, Indianapolis, USA (2002)

[10] Lim YI, Chang CS, Jorgensen SB, Comput. Chem. Eng., 28(8), 1309 (2004)

[11] Pais LS, Loureiro JM, Rodrigues AE, AIChE J., 44(3), 561 (1998)

[12] Lim YI, Jorgensen SB, Chem. Eng. Sci., 59(10), 1931 (2004)