Precipitation polymerization of 2-(methacryloyloxyethyl) trimethyl ammonium chloride (DMC)-co-acrylamide (AM) [poly(AM-DMC)] has been successfully performed in potassium carbonate (K2CO3)-water media by plasma initiation. K2CO3 solution was selected because not only the higher solubility of AM and DMC comparing with that of poly(AM-DMC), but the higher intrinsic viscosity of poly(AM-DMC) could be obtained. A set of experiments was performed using different K2CO3 concentration (from 50 down to 10% (w/w)), thus the precipitation architecture was not obtained below 20% (w/w). And particles size, particles size distribution (7-120 [tm), and intrinsic viscosity of poly(AM-DMC) (ranging up to 455 cm(3)/g) were also summarized in this article. (C) 2007 Wiley Periodicals, Inc.