This Letter reports the, first kinetic study of 2-butoxy radicals to employ direct monitoring of the radical. The reactions of 2-butoxy with Oz and NO are investigated using laser-induced fluorescence (LIF). The Arrhenius expressions for the reactions of 2-butoxy with NO (k(1)) and O-2 (k(2)) in the temperature range 223-311 K have been determined to be k(1) = (7.50 +/- 1.69) x 10(-12) x exp((2.98 +/- 0.47) kJ mol(-1)/RT) cm(3) molecule(-1) s(-1) and k(2) = (1.33 +/- 0.43) x 10(-15) x exp((5.48 +/- 0.69) kJ mol(-1)/RT) cm(3) molecule(-1) s(-1). No pressure dependence was found for the rate constants of the reaction of 2-butoxy with NO at 223 K between 50 and 175 Torr.