A noisy biological system is applied to investigate the influence of coupling on the internal stochastic resonance. It is found that the internal stochastic resonance could be transferred by coupling, and the enhancement and suppression of the stochastic resonance could be realized by controlling the coupling strength at proper range. The explicit internal signal stochastic resonance without tuning occurs. An appropriate coupling strength is found to enhance the propagation of the internal stochastic resonance most effectively with the increment of the external noise. (c) 2005 Elsevier B.V. All rights reserved.