Chemistry Letters, Vol.29, No.4, 328-329, 2000
Unexpected formation of novel [4.3.3]propellane-type trilactone by dehydration of aliphatic tetracarboxylic acid
Dehydration of 3-carboxy-3-(carboxymethyl)hexanedioic acid with excess acetic anhydride resulted in the formation of a novel propellane-type trilactone (orthoester), 2,9,10-trioxa[4.3.3]propellane-3,8,1 1-trione. This is the first one-step synthesis of a propellane from an acyclic compound.