Fluoride ion-mediated intramolecular aldol cyclization of 7-(t-butyldimethylsiloxy)-7-octenal

Hachiya I; Kobayashi N; Kijima H; Pudhom K; Mukaiyama T

Chemistry Letters, Vol.29, No.8, 932-933, 2000

Hachiya I, Kobayashi N, Kijima H, Pudhom K, Mukaiyama T

Polyoxy 8-membered ring compound was synthesized in moderate to good yields by intramolecular aldol cyclization of 7-(t-butyldimethylsiloxy)-7-octenal using tetrabutylammonium fluoride (TBAF).