Chemistry Letters, Vol.29, No.8, 948-949, 2000
Preparation, conformation and reaction of medium-sized [1.n.n]metacyclophanes
A series of metacyclophanes consisting of three aromatic rings have been prepared. The detailed study of their conformational properties by means of the NMR spectroscopy and the X-ray analysis confirmed the "n,m-alternate(folded-inwards)" and "n,m-alternate(cone-like)" conformations. Two conformers of 3a exhibited a different reactivity in demethylation by BBr3.