Chemistry Letters, Vol.31, No.2, 160-161, 2002
An intriguing effect of polymer-bound lithium amides in catalytic enantioselective rearrangement of meso-epoxides mediated by chiral lithium amides
Polymer-bound lithium dialkylamides were prepared from the corresponding polymer-bound amines and butyllithium. The reagent was successfully employed as an in situ regenerating agent of a chiral lithium amide in a catalytic enantioselective rearrangement of meso-epoxides, and chiral allylic alcohols were obtained in up to 95% ee.