Chemistry Letters, Vol.31, No.2, 200-201, 2002
Duplex stabilizing effect and nuclease resistant property of novel oligonucleotides containing C-2 branched polyamine-bearing deoxyinosine derivative
Novel oligodeoxyribonucleotides containing a C-2 branched polyamine-bearing deoxyinosine moiety at either inside-region or the 5'-terminus of the sequence exhibited enhanced nuclease resistant property. Among them, only the oligomers having the modified deoxyinosine residue at inside-region brought about duplex stabilizing effect upon mixing with the complements.