Chemistry Letters, Vol.31, No.3, 368-369, 2002
A novel, one-pot synthesis of alpha-C-cyanohydrazines in the presence of lithium perchlorate/diethylether solution (5.0 M)
Condensation of N, N-dimethylhydrazine, an aldehyde in lithium perchlorate/diethylether solution (5.0 M) gave N, N-dimethylhydrazone, which were treated with trimethylsilyl-cyanide to afford alpha-C-cyanohydrazine. These compounds are important precursors of nitrogen-substituted reagents.