Colorimetric detection of human lung carcinoma cell by enlarging Au-nanoparticles in situ

Ma ZF; Liang R; Jiang WL; Zhou TH; Chen ZH; Duan MX; Tang JT; Sui SF

Chemistry Letters, Vol.31, No.6, 570-571, 2002

Colorimetric detection of human lung carcinoma cell by enlarging Au-nanoparticles in situ

Ma ZF, Liang R, Jiang WL, Zhou TH, Chen ZH, Duan MX, Tang JT, Sui SF

A new approach to the colorimetric detection of human lung carcinoma cell by enlarging Au-nanoparticles in situ has been reported. The results show that the sensitivity of detecting lung carcinoma cell is ca. 100 cell mL(-1). By enlarging Au-nanoparticles immobilized on the nitrocellulose strips in situ with 0.01% HAuCl4 and 0.4 mM NH2OH, detection of lung carcinoma cell by naked eye is available. It will be of great significance in rapid and early clinical diagnosis.