Chemistry Letters, Vol.31, No.12, 1234-1235, 2002
A novel three-component pseudo-polymorphism in the cholamide inclusion crystals promoted by the combination of organic guest and water
Cholamide (1) exhibits a novel pseudopolymorphism in a three-component system composed of 1, acetonitrile, and water. Recrystallization of 1 from a guest solution composed of an equal amount of acetonitrile and water gave one polymorph (triangular, 1 : 1 : 1 molar ratio of 1 : acetonitrile : water). Diminished water in the guest solution provided the other polymorph (bilayer, 1 : 1 : 2).