Chemistry Letters, Vol.32, No.1, 88-89, 2003
Photo-enhancement of transfection efficiency with a novel azobenzene-based cationic lipid
The transfection efficiency of a novel photoresponsive cationic lipid having an azobenzene structure can be controlled by UV irradiation. After DNA complexes pass through the cell membrane by endocytosis, trans to cis isomerization of the azobenzene structure would destabilize the vesicle membrane.