Chemistry Letters, Vol.33, No.6, 714-715, 2004
Structure, synthesis, and biological activity of 14-methoxy-1,2-dehydrocacalol methyl ether, a new modified furanoeremophilane type sesquiterpene from Trichilia cuneata
A new modified furanoeremophilane type sesquiterpene, (+)-14-methoxy-1,2-dehydrocacalol methyl ether (2), isolated from Trichilia cuneata exhibited inhibitory activity for mitochondrial lipid peroxidation. The first total synthesis of (+/-)-2 and two related sesquiterpenes, (+/-)-14-hydroxycacalol methyl ether (7) and 14-methoxydehydrocacalohastine (8), has also been achieved.