화학공학소재연구정보센터
Chemistry Letters, Vol.33, No.7, 942-943, 2004
Synthesis of (+/-)-sordaricin
(+/-)-Sordaricin, the aglycon of antifungal sordarin, was synthesized starting from bicyclo[5.3.0]decan-3-one derivative. The strained bicyclo[2.2.1]heptene framework of sordaricin was constructed by the palladium-catalyzed intramolecular Tsuji-Trost reaction.