Genome sequencing projects are providing researchers with an unprecedented wealth of information. This information has the potential to make a deep impact on how experiments are planned and the physiology of living organisms is investigated. One field where the availability of genome sequence has not been thoroughly exploited yet is bioinorganic chemistry. The latter discipline deals with the interaction of biological molecules with inorganic compounds. In this review we give an overview of some aspects of the interplay of genome sequencing projects and bioinorganic chemistry.