Chemistry Letters, Vol.34, No.4, 470-471, 2005
Application of organocerium reagents for the efficient conversion of Z-alpha,beta-unsaturated Weinreb amides to Z-alpha,beta-unsaturated ketones
The reactions of Z-rich unsaturated Weinreb amides with organolithium and organocerium reagents were examined. Taking in consideration both the extent of geometry retention and cleanness of the reaction, organocerium reagents were more effective for the conversion to Z-alpha,beta-unsaturated ketones.