Regenerated cellulose from cellulose triacetate was regioselectively converted into its lipophilic amino and dithiocarbarnate derivatives to prepare novel solvent extraction reagents with series of substitutions and deoxy substitution reaction. The 6-deoxydithiocarbamate-2,3-didecyl cellulose prepared in this work significantly demonstrated the high lipophilicity coupled with high selectivity for PGM ions and also to the Cu(II) over Ni(II) and Zn(II) in liquid-liquid extraction.