Chemistry Letters, Vol.35, No.11, 1264-1265, 2006
Introduction of F3-threonine to the hexapeptide, DSLET: Investigation of the effect of fluorine atoms toward peptidic conformations
Introduction of trifluoromethyl-containing threonine to the target hexapeptide, Tyr-D-Ser-Gly-Phe-Leu-Thr (DSLET), led to the apparent conformational alteration due to the electron-withdrawing effect of the CF3 group when compared with the original DSLET on the basis of their NOESY spectra.