The vapour phase synthesis of quinoline from aniline and glycerol (1:2 mole ratio) in a single step was investigated over ZnO-Cr2O3, CuO-ZnO/Al2O3, MoO3-V2O5/Al2O3 and NiO-MoO3/Al2O3 catalysts in the presence of air at 623-723 K under normal atmospheric pressure. Among these catalysts investigated, the CuO-ZnO/Al2O3 combination effectively performed this reaction with high activity and selectivity.