Journal of Molecular Catalysis A-Chemical, Vol.159, No.2, 423-427, 2000
1,10-phenanthrolines derived from natural occurring ketones as ligands for asymmetric catalysis: enantioselective palladium catalyzed allylic substitution
A number of chiral C-1-symmetric 1,10-phenanthrolines derived from naturally occurring ketones were assessed in the enantioselective palladium catalyzed allylic alkylation of 1,3-diphenylprop-2-enyl acetate with dimethylmalonate. Enantioselectivity up to 96% was obtained with a new 1,10-phenanthroline derived from 5 alpha-cholestan-4-one.