Coupling reactions between acyl chlorides and Grignard reagents in the presence of a supported Fe(III)-complex

Dell'Anna MM; Mastrorilli P; Nobile CF; Marchese G; Taurino MR

Journal of Molecular Catalysis A-Chemical, Vol.161, No.1-2, 239-243, 2000

DOI10.1016/S1381-1169(00)00268-5 Export Citation

Coupling reactions between acyl chlorides and Grignard reagents in the presence of a supported Fe(III)-complex

Dell'Anna MM, Mastrorilli P, Nobile CF, Marchese G, Taurino MR

The polymer-supported Fe(III) complex obtained by copolymerization of Fe(AAEMA)(3) [AAEMA(-) = deprotonated form of 2-(acetoacetoxy) ethyl methacrylate] with suitable acrylamides facilitates the coupling reaction between acyl chlorides and Grignard reagents, affording ketones with yields up to 96%.

Keywords:coupling reactions;Grignard reagents;ketones;acyl chlorides;supported catalysts