Journal of Molecular Catalysis A-Chemical, Vol.236, No.1-2, 216-219, 2005
Natural HEU type zeolite catalyzed Biginelli reaction for the synthesis of 3,4-dihydropyrimidin-2(1H) one derivatives
A new method for Biginelli reaction via heterogenous catalyst has been developed. This method uses natural Heulandite type zeolite (HTMA) as a catalyst for the one pot condensation of an aldehyde, urea and a 1,3-dicarbonyl compound under mild conditions in excellent yields. (c) 2005 Elsevier B.V. All rights reserved.