A highly effective method for palladium-catalyzed Suzuki-Miyaura coupling of aryl bromides and arylboronic acids using novel 2(diphenylphosphino) benzaldoxime ligand was developed. The new catalytic system based on Pd(OAc)(2) and the readily prepared and air stable ligand afforded high turnover numbers (up to 10(4)) for a variety of substrates. (c) 2005 Elsevier B.V. All rights reserved.