Journal of Molecular Catalysis A-Chemical, Vol.247, No.1-2, 159-161, 2006
A simple, economical, and highly efficient synthesis of beta-hydroxynitriles from epoxide under solvent free conditions
A simple, rapid, and highly regioselective green protocols for the synthesis of beta-hydroxylnitriles by the direct reaction of epoxides with trimethylsilyl cyanide in the presence of catalytic amount of lithium perchlorate Linder solvent free conditions in high to quantitative yield is reported. (c) 2005 Elsevier B.V. All rights reserved.