Journal of Molecular Catalysis A-Chemical, Vol.254, No.1-2, 78-84, 2006
Exploiting catalyst characteristics: A protocol for increasing diastereoselectivity in a double ring-closing metathesis reaction
A procedure for obtaining increased selectivity in a diastereoselective double ring-closing metathesis reaction is presented. The key to success was design of a substrate, which directed the reaction mechanism through a selective pathway and use of a suitable catalyst combination to achieve the desired balance between reactivity and selectivity. (c) 2006 Elsevier B.V. All rights reserved.