Silica supported perchloric acid: A mild and highly efficient heterogeneous catalyst for the synthesis of poly-substituted quinolines via Friedlander hetero-annulation

Narasimhulu M; Reddy TS; Mahesh KC; Prabhakar P; Rao CB; Venkateswarlu Y

Journal of Molecular Catalysis A-Chemical, Vol.266, No.1-2, 114-117, 2007

DOI10.1016/j.molcata.2006.10.049 Export Citation

Silica supported perchloric acid: A mild and highly efficient heterogeneous catalyst for the synthesis of poly-substituted quinolines via Friedlander hetero-annulation

Narasimhulu M, Reddy TS, Mahesh KC, Prabhakar P, Rao CB, Venkateswarlu Y

Silica supported perchloric acid (HClO4-SiO2) is found to be a heterogeneous recyclable catalyst for the rapid and efficient synthesis of various poly-substituted quinolines in the Friedldnder condensation of 2-aminoarylketones with carbonyl compounds and P-keto esters at ambient temperature. The catalyst can be reused at least three times. (c) 2006 Elsevier B.V. All rights reserved.

Keywords:quinolines;Friedlander reaction;silica supported perchloric acid;heterogeneous catalyst