The permeation experiments of polyetherurethane membranes were studied by using 7 different alcohols in aqueous solution. The results indicated that water flux, J_w (mol/cm²·sec) and hydraulic permeability coefficient, K_w (mol/cm·sec·atm) wire increased with temperature, pressure and molecular weight of polyethylene glycol. Separation of solute alcohol were decreased with increasing the Taft number, σ^*, acidity, Δν_s cm^-2, and steric parameter, E^s of alcohol, in the order, t-butanol> sec-butanol> iso-butanol> iso-propanol> n-butanol> n-propanol> ethanol. It was also shown that the relative hydrogen-banding ability of the solute affected the preferential sorption of solute at the membrane surface. The effect of non-polar parameter, _s(H₂0) on alcohol separations increased with increasing molecular weight of alcohol and decreased in the order t-> sec-> iso-> n-, when the molecular weight was same.