A conception of inhomogeneous locally random distribution of microdefects in crystalline solids is proposed. A method to calculate some physical properties of solids containing inhomogeneously distributed defects is developed. A contribution of this inhomogeneity to a series of physical properties is calculated and discussed. This contribution exceeds that of homogeneously distributed defects by the orders of magnitude. A. contribution of the inhomogeneity to electric conductivity, Hall effect and magnetoresistance is calculated. Elastic energy and volume of inhomogeneously dislocated crystal are regarded. It was shown that the relaxation of the elastic energy of random dislocations during propagation of a crack facilitates the process. These results explained a phenomenon of lamination of overdeformed metals.