Junctions between metal, semiconductor and superconductor materials seem to be promising for their application as electronic devices, microelectronic devices and high power transmission. We fabricated Ag/Tl-Ba-Ca-CuO/CdSe nanostructures by using dc electro-deposition technique. The TI-Ba-Ca-Cu alloyed thin films were deposited onto silver substrate at a constant potential of -1.25 V and then oxidized electrochemically at a potential of +0.7 V with respect to saturated calomel electrode (SCE) from 1 N KOH solution. Semiconducting CdSe was subsequently deposited onto superconducting system at a constant potential of -0.6V with respect to SCE. Particle size confirmed the presence of nanostructure, of the order of 27 nm. The sizeable change of the electrical conductivity was obtained by irradiating the nanostructure with red He-Ne laser (lambda = 632.8 nm) for different periods.