The Karr column is an apparatus for countercurrent liquid-liquid extraction equipped with reciprocating perforated plates, This arrangement improves local mass transfer between the organic and aqueous phases. This system has been reported to be highly nonlinear and potentially difficult to control : most previous studies have involved SISO control for this arrangement with some MIMO exceptions. This paper describes an experimental study which included instrumentation of a Karr extraction column, identification of empirical dynamic models, design of a full matrix (2x2) IMC controller and its implementation on the process using a computer with MATLAB/SIMULINK(R) as the interface.