Review: Biomedical applications of perfluorinated compounds, which are either dense white powders or colorless, odorless liquids, are based on their gastransport capabilities and include resuscitation fluids, microcirculatory support in ischaemic tissues, tumor sensitizers, contrast agents, and the preservation of organs or limbs prior to transplantation. The various formulations, which also contain surfactants, are described with reference to their biocompatibility and modes of use.