Polyglycolide (poly(hydroxyacetic acid)) with wide variability of pore size can be prepared by combination of a solid-state polymerization reaction and addition of sodium chloride crystals. The solid state reaction leads to a composite of polyglycolide and NaCl. The latter can be washed out with water leaving behind porous polyglycolide with interconnected pores in the micrometer range. To achieve a higher porosity and to induce larger pores, additional coarse sodium chloride was added before polymerization. This opens a way to functionally graded polyglycolide resembling natural bone that should have a potential as bone substituting material.