Biochemical and Biophysical Research Communications, Vol.295, No.1, 14-16, 2002
Sensitivity enhancement of DNA sensors by nanogold surface modification
A novel amplified microgravimetric gene sensing system was developed using quartz crystal microbalance modified by gold nanoparticles anchored on its 1,6-hexanedithiol modified gold electrode surface, and ultrasensitive detection of DNA hybridization was accomplished at the level of at least 2 x 10(-16) M. (C) 2002 Elsevier Science (USA). All rights reserved.