A full-swing pentacene organic thin-film transistor (OTFT) inverter, which is composed of an enhancement-mode driver and a depletion-mode load, is proposed and confirmed at the discrete device level. The depletion-mode OTFT can be easily converted to the enhancement-mode by adding a thin PNINIA layer between insulator and pentacene to the depletion-mode fabrication sequence. It is demonstrated that the proposed inverter shows a full-swing characteristic, large inverting gain and high noise margin with only two OTFTs. (c) 2006 Elsevier Ltd. All rights reserved.