This work studies the influence of Fe, Fe-Mo, Co-Mo, and Ni-Mo catalysts on the coprocessing of a Lignite from the Bergueda (Catalonia, Spain) with a vacuum residue of petroleum. Given the high mineral matter content of this Lignite, it was demineralized to prevent any interference with the catalyst performance. A set of supported Fe-based catalysts as well as two commercial hydroprocessing catalysts were tested. The experimental results show that coal conversion increases with all catalysts, although those containing molybdenum yield the largest values (50-60%). The percentage of iron in the catalyst does not have a strong influence on this conversion, suggesting functional problems. Significantly high coal conversions are also obtained in experiments with alumina (approximate to 40%) or without catalyst (approximate to 44%), suggesting that the demineralization process causes fragmentation of the coal structure. The production of oils is larger with the Mo-based catalysts (19-25%) and on the order of 8% for the Fe-based catalysts.