In order to study the possibility of using supercritical CO2 to concentrate tocopherols from soybean oil de-odorizer distillate (DOD), the binary phase equilibrium data for methyl oleate-CO2 and alpha-tocopherol-CO2 were measured at 313.15-353.15 K in the pressure ranges of 5-23 MPa for methyl oleate and 5-30 MPa for alpha-tocopherol, respectively. The measured data were well correlated using the Soave-Redlich-Kwong (SRK) equation of state (EOS) with the Adachi-Sugie (AS) mixing rule. The solubilities and distribution coefficients of methyl oleate and alpha-tocopherol in CO2 were investigated. Finally, on the basis of these results, a conclusion was preliminarily drawn, supercritical CO2 can be used to concentrate natural tocopherols from the esterified DOD in the experimental range investigated. In addition, the critical points of methyl oleate-CO2 at three temperatures were estimated. (C) 2003 Elsevier B.V. All rights reserved.