The properties of light rare earth Nd substitution for heavy rare earth Dy in Dy3Fe5O12 (DyIG) garnet ferrite have been studied. The NdxDy3-xFe5O12 (x = 0, 0.25. 0.5, 0.75 and 1) (Nd:DyIG) garnet powders were prepared by sol-gel autocombustion followed by heat treatment. The structure and the magnetic properties of the annealed powders were measured with X-ray diffraction (XRD), the Fourier Transform Infrared (FT-IR) and the Physical Properties Measurement System (PPMS) techniques. The experimental results indicate that a single Nd:DyIG garnet phase structure can be obtained after the samples annealed above 800 degrees C. With the Nd substitution content increasing. the average lattice constants of the sample, the a-d super-exchange interaction strengthens and the magnetization of unit cell increase. The maximum saturation magnetization is 13.86 emu/g for x = 1, and coercive force is about 136 Oe, for x = 0.75. The reason of increasing in magnetization with Nd substitution is also discussed.