Advanced Materials, Vol.19, No.22, 3791-3791, 2007
Aggregation-enhanced fluorescence in organically modified silica nanoparticles: A novel approach toward high-signal-output nanoprobes for two-photon fluorescence bioimaging
Phase-separated nanoaggregation of a highly loaded 9,10-bis[4'-(4"-aminostyryl)-styryl]anthracene dye in organically modified silica (ORMOSIL) nanoparticles boosts intracellular two-photon fluorescence signal by virtue of enhanced two-photon absorption and emission, high chromophore number density in the nano-space, and noninvasive cellular uptake.