A number of heterogeneously catalyzed reactions, mainly gas-phase reactions, have been performed previously at a laboratory scale and a successful proof of concept was achieved. Since the beginning of this century, there has been a shift in focus on the transfer from laboratory scale to production scale. In particular, this review deals with the technical concepts and economic aspects involved in such a shift. Heterogenously catalyzed gas-phase and liquid-phase processes are discussed separately. The preparation of wall catalysts is a key technology in both cases and is described in an additional subsection. Finally, an evaluation of the developmental status is given.