Chemistry Letters, Vol.36, No.12, 1436-1437, 2007
Synthesis of C-2-symmetric sulfide and its first application in highly enantioselective synthesis of chiral aziridines
A C-2-symmetric sulfide 6 has been synthesized from cheap L-tartaric acid. It was found that sulfide 6 could perform a tandem reaction with benzyl bromide and tosyl imines to give (2S.3S)-aziridines 9a-9g with good to excellent enantioseletivities (up to 96% ee).