In this work, photodegradation of bisphenol A (BPA) in water was investigated under an UV sterilization lamp (lambda = 254 nm). The photodegradation kinetics of 5.0 similar to 50.0 mg/L BPA in aqueous solutions was found to follow first-order law. The influencing factors such as the pH value, light source, different water media and salinity on photodegradation of BPA were studied in detail.