화학공학소재연구정보센터
홈 로그인 로그아웃 연락처 사이트맵
Macromolecular Research, Vol.17, No.5, 307-312, May, 2009
Export Citation
Relative Parameter Contributions for Encapsulating Silica-Gold Nanoshells by Poly(N-isopropylacrylamide-co-acrylic acid) Hydrogels
Min-Yim Park, Sera Lim, Sang-Wha Lee†, and Sang-Eun Park1
  • Department of Chemical & Bio Engineering, Kyungwon University, Gyeonggi-do 461-701, Korea
  • 1Advanced Energy Materials Processing Laboratory, Korea Institute of Science and Technology, Seoul 130-650, Korea
E-mail:
Core-shell hydrogel nanocomposite was fabricated by encapsulating a silica-gold nanoshell (SGNS) with poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAM-co-AAc) copolymer. The oleylamine-functionalized SGNS was used as a nanotemplate for the shell-layer growth of hydrogel copolymer. APS (ammonium persulfate) was used as a polymerization initiator to produce a hydrogel-encapsulated SGNS (H-SGNS). The amounts of NIPAM (N-isopropylacrylamide) monomers were optimized to reproduce the hydrogel-encapsulated SGNS. The shell-layer thickness was increased with the increase of polymerization time and no further increase in the shell-layer thickness was clearly observed over 16 h. H-SGNS exhibited the systematic changes of particle size corresponding to the variation of pH and temperature, which was originated from hydrogen-bonding interaction between PNIPAM amide groups and water, as well as electrostatic forces attributed by the ionization of carboxylic groups in acrylic acid.
Keywords:gold nanoshell;hydrogel;poly(N-isopropylacrylamide);plasmon resonance.
  1. Ramanan RMK, Chellamuthu P, Tang LP, Nguyen KT, Biotechnol. Prog., 22(1), 118 (2006)
  2. Lee JW, Lee DS, Kim SW, Macromol. Res., 11(3), 189 (2003)
  3. Qui Y, Park K, Adv. Drug Deliver. Rev., 53, 321 (2001)
  4. Atta AM, Maysour NE, Arndt KE, J. Polym. Res., 13, 53 (2006)
  5. Ma J, Xu Y, Zhang Q, Zha L, Liang B, Colloid Polym. Sci., 285, 479 (2007)
  6. Kim JH, Lee TR, Polym. Mater. Sci. Eng., 90, 637 (2004)
  7. Hirokawa Y, Tanaka T, J. Chem. Phys., 81, 6379 (1984)
  8. Lee JW, Lee DS, Kim SW, Macromol. Res., 11(3), 189 (2003)
  9. Schild HG, Prog. Polym. Sci., 17, 163 (1992)
  10. Snowden MJ, Chowdhry BZ, Vincent B, Morris GE, J. Chem. Soc. Faraday Trans., 92, 5013 (1996)
  11. Kim JH, Lee TR, Drug Dev. Res., 67, 61 (2006)
  12. Sun Y, Xia Y, Anal. Chem., 74, 5297 (2002)
  13. Pham T, Jackson JB, Halas NJ, Lee TR, Langmuir, 18(12), 4915 (2002)
  14. Sershen SR, Mensing GA, Ng M, Halas NJ, Beebe DJ, West JL, Adv. Mater., 17(11), 1366 (2005)
  15. Zhao XL, Ding XB, Deng ZH, Zheng ZH, Peng YX, Long XP, Macromol. Rapid Commun., 26(22), 1784 (2005)
  16. Stober W, Fink A, J. Colloid Interf. Sci., 26, 62 (1968)
  17. Park S, Park M, Han P, Lee S, J. Ind. Eng. Chem., 13(1), 65 (2007)
  18. Park SE, Park MY, Han PK, Lee SW, Bull. Korean Chem. Soc., 27, 1341 (2006)
  19. Giannuzzi LA, Steve FA, Micron, 30, 197 (1999)
  20. Westcott SL, Oldenburg SJ, Lee TR, Halas NJ, Langmuir, 14(19), 5396 (1998)
  21. Tam F, Halas N, Progress in Organic Coatings, 47, 275 (2003)
  22. Saunders BR, Vincent B, Adv. Colloid Interf. Sci., 80, 1 (1999)
  23. Qiu Y, Park K, Adv. Drug Deliver. Rev., 53, 321 (2001)
  24. Kotal A, Mandal TK, Walt DR, J. Polym. Sci. A: Polym. Chem., 43(16), 3631 (2005)
  25. Kim JH, Lee TR, Intl. Conf. on Biomedical and Pharmaceutical Engineering 2006 (ICBPE 2006), p. 271-275