The aim of the article was to evaluate the microstructural parameters of Cu-Al2O3 dispersion strengthened materials with different volume fraction of Al2O3 phase. For analyses of dispersoids Al2O3, the extraction carbon replica was used. The distribution of Al2O3 particles in the matrix was estimated by three methods (quadrant count method, polygonal method, and by interparticle distances), these methods showed that particle distribution in material with 1 vol.% of Al2O3 is very close to the Poisson point process (PPP), which is a model of randomly distributed points. Particle distributions in materials with 8 and 10 vol.% of Al2O3 achieve features of regularity proved mainly by the spherical contact distance.