Titanate nanotubes were successfully synthesized via a hydrothermal process with the assistance of surfactant. These nanotubes with average length of several hundred nanometers and diameter of 10 nm were employed to modify glass carbon electrode and measure dopamine via electrochemistry method. The experiments showed ideal reversibility in cyclic voltammetry, which might be due to the decrease of the overvoltage of the electrode and increase of electron transference. The results illustrated the potential application in the detection of dopamine.