The effect of the interaction between nanopore and chain segment on the translocation of polymer chains through an interacting nanopore from a confined environment (cis side, high concentration of chain) to a spacious environment (trans side, zero concentration) was studied by using dynamic Monte Carlo simulations. Results showed that a moderate attractive pore-polyrner interaction accelerates the translocation of chain. The optimal interaction at which translocation is the fastest increases with the concentration of chain on the cis side. The dependence of microscopic behaviors of chain translocation on the interaction was investigated. (C) 2007 Elsevier Ltd. All rights reserved.