A new correlation equation for predicting the filter coefficient under unfavorable deposition conditions is presented. By adopting the triangular network model of using the Brownian dynamic simulation method, as the sum of four individual deposition mechanisms, e.g., the Brownian diffusion, the DLVO interactions, the gravitational force, and the interception, the correlation equation is obtained by regressing against a broad range of parameter values governing particle deposition in deep bed filtration. The new correlation equation is able to describe previous experimental results well, especially for those submicro particles with significant Brownian motion behavior.