5-[o-(4-Bromine amyloxy)phenyl]-10,15,20-triphenylporphrin (o-BrPETPP) was electropolymerized on a glassy carbon electrode (GCE), and the electrocatalytic properties of the prepared film electrode response to dopamine (DA) oxidation were investigated. A stable o-BrPETPP film was formed on the GCE under ultrasonic irradiation through a potentiodynamic process in 0.1 M H2SO4 between -1.1 V and 2.2 V versus a saturated calomel electrode (SCE) at a scan rate of 0.1 V s(-1). The film electrode showed high selectivity for DA in the presence of ascorbic acid (AA) and uric acid (UA), and a 6-fold greater sensitivity to DA than that of the bare GCE. In the 0.05 mol L-1 phosphate buffer (pH 6.0), there was a linear relationship between the oxidation current and the concentration of DA solution in the range of 5 x 10(-7) mol L-1 to 3 x 10(-5) mol L-1. The electrode had a detection limit of 6.0 x 10(-8) mol L-1(S/N = 3) when the differential pulse voltammetric (DPV) method was used. In addition, the charge transfer rate constant k = 0.0703 cm s(-1), the transfer coefficient alpha = 0.709, the electron number involved in the rate determining step n(alpha)=0.952, and the diffusion coefficient D-o= 3.54 10(-5) cm(2) s(-1) were determined. The o-BrPETPP film electrode provides high stability, sensitivity, and selectivity for DA oxidation. (c) 2008 Elsevier Ltd. All rights reserved.